Umirolimus.90 t J23 l av
| |||
| Klinički podaci | |||
|---|---|---|---|
| AHFS/Drugs.com | Monografija | ||
| Identifikatori | |||
| CAS broj | 851536-75-9 | ||
| ATC kod | nije dodeljen | ||
| ChemSpider[1] | 24582455 | ||
| Hemijski podaci | |||
| Formula | C55H87NO14 | ||
| Mol. masa | 986,278 | ||
| SMILES | eMolekuli & PubHem | ||
| |||
| Farmakoinformacioni podaci | |||
| Trudnoća | ? | ||
| Pravni status | |||
Umirolimus je organsko jedinjenje, koje sadrži 55 atoma ugljenika i ima molekulsku masu od 986,278 Da.
Sadržaj/Садржај
- 1 Osobine
- 2 Reference
- 3 Literatura
- 4 Spoljašnje veze
Osobine[uredi - уреди | uredi izvor]
| Osobina | Vrednost |
|---|---|
| Broj akceptora vodonika | 14 |
| Broj donora vodonika | 2 |
| Broj rotacionih veza | 11 |
| Particioni koeficijent[2] (ALogP) | 6,9 |
| Rastvorljivost[3] (logS, log(mol/L)) | -11,7 |
| Polarna površina[4] (PSA, Å2) | 193,7 |
Reference[uredi - уреди | uredi izvor]
- ↑ Hettne KM, Williams AJ, van Mulligen EM, Kleinjans J, Tkachenko V, Kors JA. (2010). "Automatic vs. manual curation of a multi-source chemical dictionary: the impact on text mining". J Cheminform 2 (1): 3. PMID 20331846. doi:10.1186/1758-2946-2-3.
- ↑ Ghose, A.K., Viswanadhan V.N., and Wendoloski, J.J. (1998). "Prediction of Hydrophobic (Lipophilic) Properties of Small Organic Molecules Using Fragment Methods: An Analysis of AlogP and CLogP Methods". J. Phys. Chem. A 102: 3762–3772. doi:10.1021/jp980230o.
- ↑ Tetko IV, Tanchuk VY, Kasheva TN, Villa AE. (2001). "Estimation of Aqueous Solubility of Chemical Compounds Using E-State Indices". Chem Inf. Comput. Sci. 41: 1488–1493. PMID 11749573. doi:10.1021/ci000392t.
- ↑ Ertl P., Rohde B., Selzer P. (2000). "Fast calculation of molecular polar surface area as a sum of fragment based contributions and its application to the prediction of drug transport properties". J. Med. Chem. 43: 3714–3717. PMID 11020286. doi:10.1021/jm000942e.
Literatura[uredi - уреди | uredi izvor]
- Hardman JG, Limbird LE, Gilman AG. (2001). Goodman & Gilman's The Pharmacological Basis of Therapeutics (10 izd.). New York: McGraw-Hill. DOI:10.1036/0071422803. ISBN 0-07-135469-7. http://books.mcgraw-hill.com/medical/goodmanandgilman/.
- Thomas L. Lemke, David A. Williams, ur. (2007). Foye's Principles of Medicinal Chemistry (6 izd.). Baltimore: Lippincott Willams & Wilkins. ISBN 0-7817-6879-9. http://www.lww.com/productTOC/?ISBN=978-0-7817-6879-5.
Spoljašnje veze[uredi - уреди | uredi izvor]
Umirolimus na Wikimedijinoj ostavi
- Umirolimus